Macroscopic thrombi formation in the blood plasma under intensive flow conditions in vitro

Thrombus formation processes can develop very rapidly under intensive blood flow. Over a time of about ten minutes the macroscopic thrombus completely blocks the lumen of the in vitro model of the vessel. In this process, blood coagulation develops consistently: the formation of primary microclots, the formation of more large aggregates, the formation of а macrothrombus.

A more detailed description is given in our articles [Biophysics, 2018; Биофизика, 2018].